Übersicht			Auf mobile öffnen

Lieferstatus:	Auf Bestellung (Lieferzeit unbekannt)
Veröffentlichung:	April 2015
Genre:	Naturwissensch., Medizin, Technik
	Chemie / chemistry / Drug Discovery & Development / Enzyme u. Rezeptoren / Enzymes & Receptors / Physical Chemistry / Physikalische Chemie / Rezeptor / Wirkstoffforschung / Wirkstoffforschung u. -entwicklung
ISBN:	9783527335824
EAN-Code:	9783527335824
Verlag:	Wiley-Vch
Einband:	Gebunden
Sprache:	English
Serie:	#65 - Methods and Principles in Medicinal Chemistry
Dimensionen:	H 240 mm / B 170 mm / D 30 mm
Gewicht:	854 gr
Seiten:	360
Illustration:	Tabellen, schwarz-weiss, farbige Illustrationen, schwarz-weiss Illustrationen
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.