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The history of Chikungunya virus: Origin and evolution
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| Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus and belongs to the Togaviridae family (Schuffenecker et al., 2006). It causes chikungunya fever (CHIK fever), a febrile illness associated with severe arthralgia and rash (Adebajo, 1996; Deller and Russell,1967; Ligon, 2006; McGill, 1995). The alphaviruses consist of 30 species of arthropod-borne viruses, which are further subgrouped into seven serocomplexes based on serological data (Porterfield, 1980; Strauss and Strauss, 1994; Van Regenmortel et al., 2000). CHIKV belongs to the Semliki Forest virus antigenic complex that also contains the O¿Nyong Nyong, Mayaro, and Ross River viruses. Chikungunya is a Makonde word (Bantu language) meaning ¿The one which bends up¿ referring to the posture of the affected patient acquired due to excruciating pain in the joints (Robinson, 1955). |
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