Some blame the scientists, others see the hand of God, and still others claim that human arrogance and destructiveness are reaping the punishment they deserve. Jessie Lamb is an ordinary sixteen-year-old girl living in extraordinary times. As her world collapses, her idealism and courage drive her toward the ultimate act of heroism. She wants her life to make a difference. But is Jessie heroic? Or is she, as her scientist father fears, impressionable, innocent, and incapable of understanding where her actions will lead?

Set in a world irreparably altered by an act of biological terrorism, The Testament of Jessie Lamb explores a young woman's struggle to become independent of her parents. As the certainties of her childhood are ripped apart, Jessie begins to question her parents' attitudes, their behavior, and the very world they have bequeathed her.