When young Gilded Age society matron Daisy Harriman is refused a room at the Waldorf because they don’t cater to unaccompanied females, she takes matters into her own hands. She establishes the Colony Club, the first women’s club in Manhattan, where visiting women can stay overnight and dine with their friends; where strong women can discuss new ideas, take on social issues, and make their voices heard. She hires the most sought-after architect in New York, Stanford White, to design the clubhouse.

As “the best dressed actress on the Rialto” Elsie de Wolfe has an eye for décor, but her career is stagnating. So when White asks her to design the clubhouse interiors, she jumps at the chance and the opportunity to add a woman’s touch. He promises to send her an assistant, a young woman he’s hired as a draftsman.

Raised in the Lower East Side tenements, a world away from the city's elite, Nora Bromely is determined to become an architect in spite of hostility and sabotage from her male colleagues. She is disappointed and angry when White “foists” her off on this new women’s club project.

But when White is murdered and the ensuing Trial of the Century discloses the architect’s scandalous personal life, fearful backers begin to withdraw their support. It’s questionable whether the club will survive long enough to open.

Daisy, Elsie, and Nora-forming an unlikely friendship born from crisis-have nothing in common but their determination to carry on. But to do so, they must overcome not only society’s mores but their own prejudices about women, wealth, and each other. Together they strive to transform Daisy’s dream of the Colony Club into a reality, a place that will nurture social justice and ensure the work of the women who earned the nickname “Mink Brigade” far into the future.