/ Familywise Error Rate / Fisher's exact test / Information Fraction / interim analysis / Large Sample Confidence Interval / Log Viral Load / MATHEMATICS / Probability & Statistics / General / missing data / Multiple Comparison Adjustment / Nonmissing Observations / Permuted Block Randomization / Probability & statistics / Probability and statistics / randomized controlled studies / research design strategies / Response Adaptive Randomization / sample size calculation / Sample Size Recalculation / Simple Randomization / Spending Function / statistical analysis for medical research / statistical inference methods / Strong Null Hypothesis / Tipping Point Analysis / Treatment Effect Estimators / Unpaired Setting