/ Epidemiology and Medical statistics / Familywise Error Rate / Fisher's exact test / group-sequential monitoring / Information Fraction / interim analysis / Large Sample Confidence Interval / Log Viral Load / MATHEMATICS / Probability & Statistics / General / MEDICAL / Biostatistics / MEDICAL / Pharmacology / missing data / Multiple Comparison Adjustment / Multiple Comparisons / Nonmissing Observations / Permuted Block Randomization / Probability and statistics / randomization-based inference / Response Adaptive Randomization / sample size calculation / Sample Size Recalculation / sample size/power / Simple Randomization / Spending Function / Strong Null Hypothesis / Sudden Idiopathic Sensorineural Hearing Loss / Survival Analysis / Tipping Point Analysis / Treatment Effect Estimators / Unpaired Setting