Übersicht			Auf mobile öffnen

Lieferstatus:	Auf Bestellung (Lieferzeit unbekannt)
Veröffentlichung:	November 2018
Genre:	Naturwissensch., Medizin, Technik
	B / biochemistry / Chemistry and Materials Science / Chemistry, Physical and theoretical / MEDICINAL CHEMISTRY / Microscopy / Quantum & theoretical chemistry / Scientific equipment, experiments & techniques / spectroscopy / Spectroscopy and Microscopy / Spectroscopy/Spectrometry / Spectrum analysis, spectrochemistry, mass spectrometry / Theoretical and Computational Chemistry / Theoretical Chemistry
ISBN:	9783319961712
EAN-Code:	9783319961712
Verlag:	Springer Nature EN
Einband:	Gebunden
Sprache:	English
Serie:	Springer Theses
Dimensionen:	H 235 mm / B 155 mm / D 21 mm
Gewicht:	588 gr
Seiten:	238
Illustration:	XLI, 238 p. 167 illus., 74 illus. in color., schwarz-weiss Illustrationen, farbige Illustrationen
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This book explores how nuclear magnetic resonance (NMR) spectroscopy may be used for spatial structural elucidation of novel compounds from fungal and synthetic sources. Readers will discover the exciting world of NOE (nuclear Overhauser effect), RDC (residual dipolar coupling) and J-coupling constants, both short- and long range. With emphasis on obtaining structural knowledge from these NMR observables, focus is moved from solving a static 3D structure to solving the structural space inhabited by small organic molecules. The book outlines the development and implementation of two Heteronuclear Multiple Bond Correlation-type NMR experiments, and the 3D structural elucidation of multiple known and novel compounds. In addition, a new method of back-calculating RDCs (allowing for more flexible structures to be investigated), and the synthesis and evaluation of novel chiral alignment media for ab initio determination of absolute stereochemistry of small molecules using RDCs are also included. Challenges that 3D structural generation of small compounds face are also covered in this work.