Übersicht			Auf mobile öffnen

Lieferstatus:	Auf Bestellung (Lieferzeit unbekannt)
Veröffentlichung:	November 2017
Genre:	Naturwissensch., Medizin, Technik
	AAVs / B / Biomedical and Life Sciences / gene silencing / Human Genetics / Medical Genetics / Vector production
ISBN:	9781493975211
EAN-Code:	9781493975211
Verlag:	Springer EN
Einband:	Gebunden
Sprache:	English
Serie:	#1715 - Methods in Molecular Biology
Dimensionen:	H 254 mm / B 178 mm / D 27 mm
Gewicht:	8855 gr
Seiten:	380
Illustration:	XVI, 380 p. 54 illus., 44 illus. in color., schwarz-weiss Illustrationen, farbige Illustrationen
Zus. Info:	EUDR exemption - product or manufacturing materials placed on the market prior to 31.12.2025.
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This detailed volume describes a spectrum of methods and protocols that can be used for the bench-to-bedside development and evaluation of retinal gene therapy. Methods for the successful delivery of these gene therapy vector systems to the retina are examined, as well as assays to test the efficacy in vitro in cell cultures, for gene augmentation and gene editing in vivo on rodents, pigs, and monkey retinas, and on human retinal explants as well as in human clinical studies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and practical, Retinal Gene Therapy: Methods and Protocols provides a wide range of readers from students to research experts with vital information on ocular gene therapy vector technology, in vitro and in vivo biological assays, and clinical protocols, to promote further studies for the benefit of children and adults with inherited retinal disease.