This book offers an approach for multi-scale, integrated assessment of land use, water, energy, food, populations and environmental resources. The approach is based in resource accounting, providing insights through exploring the relationships between flows of goods, services, and materials, and the funds of natural, human, social, financial, physical, and economic capitals, at multiple scales. The text describes the conceptual, technical and applied aspects of the approach, using international case studies to illustrate the manner in which it can be applied and used to improve understanding of the interdependencies of land use, water, energy and food for decision making.