Übersicht			Auf mobile öffnen

Lieferstatus:	Auf Bestellung (Lieferzeit unbekannt)
Veröffentlichung:	Oktober 2016
Genre:	Naturwissensch., Medizin, Technik
	B / Biomedical and Life Sciences / Biomedical Research / Cancer Research / Drug Resistance / Medical Microbiology / Medical research / molecular biology / Molecular Medicine / Pharmacology
ISBN:	9783319381756
EAN-Code:	9783319381756
Verlag:	Springer Nature EN
Einband:	Kartoniert
Sprache:	English
Serie:	#05 - Resistance to Targeted Anti-Cancer Therapeutics
Dimensionen:	H 235 mm / B 155 mm / D
Gewicht:	4102 gr
Seiten:	248
Illustration:	XV, 248 p. 48 illus., 36 illus. in color., schwarz-weiss Illustrationen, farbige Illustrationen
Zus. Info:	Previously published in hardcover
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This volume provides a comprehensive review of resistance induced by photodynamic therapy (PDT) in tumor cells. Understanding the underlying mechanisms in this process leads to the improvement of therapeutic modality, in combination with chemotherapy, immunotherapy, and radiotherapy. Photodynamic therapy is a minimally invasive therapeutic procedure that can exert a selective or preferential cytotoxic activity toward malignant cells. The procedure involves administration of an intrinsically non-toxic photosensitizing agent (PS) followed by irradiation at a wavelength corresponding to a visible absorption band of the sensitizer. In the presence of oxygen, a series of events lead to direct tumor cell death, damage to the microvasculature, and induction of a local inflammatory reaction. Studies reveal that PDT can be curative, particularly in early stage tumors and this volume explores the potential of PDT, but also reveals strategic approaches to overcome resistance in tumor cells.