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Recent Advances in Cell Biology of Acute Leukemia: Impact on Clinical Diagnosis and Therapy
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Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 3 Artikel!
Inhalt: |
This volume gives an overview of the state of the artregarding cell-biological features of acute leukemias. Basedon survey articles and results of clinical multicenterstudies in children and adults with ALL or AML, it offers adetailed presentation concerning the significance ofimmunologic, cytogenetic and molecular-biologic analyses inthe classification of acute leukemia and the identificationof clinical risk groups. Current immunological andmolecular-biological techniques for detecting minimalresidual disease are described and their possibilities andlimitations discussed. Further main topics includepreclinical investigations and first clinical experiencewith interleukin 2-based immunotherapy in acute leukemia,biological features of new hematopoietic growth factors andrecent advanced in the molecular understanding of thegenetic defects in leukemic cells. |
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