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PtaRNA1: Plasmid, Antisense RNA, Non-Coding RNA, Proteobacteria
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available from Wikipedia or other free sources online. PtaRNA1 (plasmid
transferred antisense RNA) is a family of non-coding RNAs. Homologs of
PtaRNA1 can be found found in the proteobacteria families,
Betaproteobacteria and Gammaproteobacteria. In all cases the PtaRNA1 is
located anti-sense to a short protein coding gene. In Xanthomonas
campestris pv. vesicatoria, this gene is annotated as XCV2162. These
proteins make up the plasmid toxin family. Both PtaRNA1 and the
corrosponding gene, which only appear only in combination, have an
erratic phylogenetic distribution. The distribution of ptaRNA1 is not
congruent with the phylogeny of the host species as it is with other
sRNA families such as Yfr1 and Yfr2. This indicates that ptaRNA1 has
undergone frequent horizontal gene transfer. These observations are in
accordance with those made of Type I toxin-antitoxin systems. In Type I
toxin-antitoxin systems, the gene expression of a toxic protein is
regulated by a small non-coding RNA. |
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