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Protein Subcellular Localization Prediction: Bioinformatics, Genome Project, Eukaryote, Genome, Cytosol
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Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 2 Artikel!
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| Please note that the content of this book primarily consists of articles
available from Wikipedia or other free sources online. Protein
subcellular localization prediction involves the computational
prediction of where a protein resides in a cell. Prediction of protein
subcellular localization is an important component of
bioinformatics-based prediction of protein function and genome
annotation, and it can aid the identification of drug targets. Most
eukaryotic proteins are encoded in the nuclear genome and synthesized in
the cytosol, but many need to be further sorted before they reach their
final destination. For prokaryotes, proteins are synthesized in the
cytoplasm and some must be targeted to other locations such as to a cell
membrane or the extracellular environment. Proteins must be localized at
their appropriate subcellular compartment to perform their desired
function. Experimentally determining the subcellular localization of a
protein is a laborious and time consuming task. |
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