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Herausgeber: 
  • R. John Mayer
  • Aaron J. Ciechanover
  • Martin Rechsteiner
  • Protein Degradation Series / Protein Degradation: Vol. 4: The Ubiquitin-Proteasome System and Disease 
     

    (Buch)
    Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 2 Artikel!


    Übersicht

    Auf mobile öffnen
     
    Lieferstatus:   Auf Bestellung (Lieferzeit unbekannt)
    Veröffentlichung:  Oktober 2007  
    Genre:  Naturwissensch., Medizin, Technik 
     
    Biochemie / Biowissenschaften / Biowissenschaften, Biologie / Chemie / chemistry / Life Sciences / molecular biology / Molekularbiologie / Protein Science / Proteine
    ISBN:  9783527314362 
    EAN-Code: 
    9783527314362 
    Verlag:  Wiley-Vch 
    Einband:  Gebunden  
    Sprache:  English  
    Dimensionen:  H 240 mm / B 170 mm / D 17 mm 
    Gewicht:  626 gr 
    Seiten:  258 
    Illustration:  Tabellen, schwarz-weiss, schwarz-weiss Illustrationen, farbige Illustrationen 
    Bewertung: Titel bewerten / Meinung schreiben
    Inhalt:
    Protein degradation, the controlled break-up of cellular proteins by intracellular proteolysis, is a major component in cellular metabolism and regulates numerous cell functions, including removal of misfolded proteins, growth and cell division, DNA repair, the immune response and the stress response to emergency conditions. This final volume in the series focuses on malfunctions of the ubiquitin-proteasome system and their role in human disease. As such, it is the most comprehensive resource on this key topic in molecular cell biology, incorporating the unmatched expertise of the 2004 Chemistry Nobel laureates. The editors and authors comprise virtually all the top scientists in the field, including the pioneers of protein degradation research. From the contents: * Ubiquitin and cancer * Ubiquitin and liver cancer * Muscle atrophy * Aggresomes and human disease * Parkin and neurodegeneration * Chronic neurodegenerative diseases * Parkinson's disease * Ubiquitin and viruses * Druggability of the ubiquitin-proteasome system Required reading for molecular and cell biologists, as well as physiologists with an interest in the topic.
      
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