Übersicht			Auf mobile öffnen

Lieferstatus:	Auf Bestellung (Lieferzeit unbekannt)
Veröffentlichung:	August 2017
Genre:	Naturwissensch., Medizin, Technik
	Analytical Chemistry / Analytische Chemie / Chemie / chemistry / Clinical Pharmacology & Therapeutics / Drug Discovery & Development / Klinische Pharmakologie u. Therapie / Medical Science / Medizin / Pharmakologie / Wirkstoffforschung / Wirkstoffforschung u. -entwicklung
ISBN:	9781118916698
EAN-Code:	9781118916698
Verlag:	Wiley
Einband:	Gebunden
Sprache:	English
Serie:	Wiley Series on Pharmaceutical Science
Dimensionen:	H 240 mm / B 157 mm / D 28 mm
Gewicht:	766 gr
Seiten:	448
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability - one of the most significant hurdles in drug discovery and development. * Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability * Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development * Explains how preclinical animal models - used in preclinical testing - and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development * Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS) * Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development