The relationship between Industry 4.0 and Society 5.0 provides the basis for the expert contributions in this book, highlighting the uses of analytical methods such as mathematical optimization, heuristic methods, decomposition methods, stochastic optimization, and more. The book will prove useful to researchers, students, and engineers in different domains who encounter large scale optimization problems and will encourage them to undertake research in this timely and practical field. The book splits into two parts. The first part covers a general perspective and challenges in a smart society and in industry. The second part covers several case studies and solutions from the operations research perspective for large scale challenges specific to various industry and society related phenomena.