This book reflects developments in theory and applications rooted by Professor Polyak's fundamental contributions to constrained and unconstrained optimization, differentiable and nonsmooth functions, control theory and approximation. Each paper focuses on techniques for solving complex optimization problems in different application areas and recent developments in optimization theory and methods. Open problems in optimization, game theory and control theory are included in this collection which will interest engineers and researchers working with efficient algorithms and software for solving optimization problems in market and data analysis. Theoreticians in operations research, applied mathematics, algorithm design, artificial intelligence, machine learning, and software engineering will find this book useful and graduate students will find the state-of-the-art research valuable.