Optimal Experimental Design with R introduces experimenters to the philosophy of experimentation, and the need for good design and data collection for experiments. It gives experimenters and statisticians guidance on how to construct optimum experimental designs and calculate the sample size needed using R programs. The book contains many detailed real-world examples that show how the R programs should be used. The authors discuss variations of the regression model, including linear and nonlinear regression models. They also provide a final chapter of theoretical details for interested mathematical statisticians.