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Lieferstatus:	i.d.R. innert 5-10 Tagen versandfertig
Veröffentlichung:	Februar 2021
Genre:	Naturwissensch., Medizin, Technik
ISBN:	9783030364243
EAN-Code:	9783030364243
Verlag:	Springer International Publishing
Einband:	Kartoniert
Sprache:	English
Dimensionen:	H 254 mm / B 178 mm / D 11 mm
Gewicht:	366 gr
Seiten:	188
Zus. Info:	Paperback
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch¿s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway¿s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch¿s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books ¿ Notch Signaling in Embryology and Notch Signaling in Cancer ¿ this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.