The 1950s were a transformative, even revolutionary decade in the history of brain science. Using new techniques for probing brain activity and function, researchers in neurosurgery, psychiatry, and psychology achieved dramatic breakthroughs in the treatment of illnesses like epilepsy and schizophrenia, as well as the understanding of such faculties as memory and perception. Memory was the site of particularly startling discoveries. As one researcher wrote to another in the middle of that decade, “Memory was the sleeping beauty of the brain—and now she is awake.” Collectively, these advances prefigured the emergence of the field of neuroscience at the end of the twentieth century.

But the 1950s also marked the beginning of the Cold War and a period of transformative social change across Western society. These developments resulted in unease and paranoia. Mysterious new afflictions—none more mystifying than “brainwashing”—also appeared at this time. Faced with the discovery that, as one leading psychiatrist put it, “the human personality is not as stable as we often assume,” many researchers in the sciences of brain and behavior joined the effort to understand these conditions. They devised ingenious and sometimes transgressive experimental methods for studying and proposing countermeasures to the problem of Communist mind control. Some of these procedures took on a strange life of their own, escaping the confines of the research lab to become part of 1960s counterculture. Much later, in the early 2000s, they resurfaced in the War on Terror.

These stories, often told separately, are brought together by the historian Andreas Killen in this chronicle of the brain’s mid-twentieth-century emergence as both a new research frontier and an organ whose integrity and capacities—especially that of memory—were imagined as uniquely imperiled in the 1950s. Nervous Systems explores the anxious context in which the mid-century sciences of the brain took shape and reveals the deeply ambivalent history that lies behind our contemporary understanding of this organ.