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Autor(en): 
  • E. J. Corey
  • Yong-Jin Wu
  • Molecules Engineered Against Oncogenic Proteins and Cancer: Discovery, Design, and Development 
     

    (Buch)
    Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 3 Artikel!


    Übersicht

    Auf mobile öffnen
     
    Lieferstatus:   Auf Bestellung (Lieferzeit unbekannt)
    Veröffentlichung:  August 2023  
    Genre:  Naturwissensch., Medizin, Technik 
     
    Chemie / chemistry / Medical Science / Medizin / ORGANIC CHEMISTRY / Organische Chemie / Pharmaceutical & Medicinal Chemistry / Pharmacology & Pharmaceutical Medicine / Pharmakologie / Pharmakologie u. Pharmazeutische Medizin / Pharmazeutische u. Medizinische Chemie
    ISBN:  9781394207084 
    EAN-Code: 
    9781394207084 
    Verlag:  Wiley 
    Einband:  Gebunden  
    Sprache:  English  
    Dimensionen:  H 285 mm / B 224 mm / D 27 mm 
    Gewicht:  836 gr 
    Seiten:  400 
    Bewertung: Titel bewerten / Meinung schreiben
    Inhalt:
    A comprehensive review of the latest molecular advances in cancer treatment Featuring 91 total small molecule kinase/KRAS inhibitors, 80 of which are FDA-approved, Molecules Engineered Against Oncogenic Proteins and Cancer documents the recent scientific advances that have transformed one of medicine's most challenging areas--cancer treatment. Most of these inhibitors specifically block oncogene-induced carcinogenic proteins with results that have dramatically advanced the treatment of cancer. In addition, the structural formulas of more than 100 kinase/KRAS inhibitors in clinical trials are presented. With a very well-known chemist as an author, Molecules Engineered Against Oncogenic Proteins and Cancer includes information on: * Each molecule's structure, function of the kinase target and relevance to cancer, the drug discovery process, and molecular details of drug action * Mutated protein kinases as oncoproteins and targets for inhibition, along with the details of discovery for each antitumor antikinase agent * History of oncoprotein inhibitors and their role in advancing the treatment and understanding of cancer * The discovery process as a whole, effective strategies for innovation, ongoing challenges, and a glimpse of the future of the field Combining the most significant recent discoveries in a unique and useful way, Molecules Engineered Against Oncogenic Proteins and Cancer is an essential resource for researchers and students in bioscience, medicine, chemistry, and oncology as well as for those at industrial companies involved in therapeutic discovery.

      



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