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Lungscapes
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| The invention of an instrument called the OPTICAL
MICROSCOPE and the new possibilities it offered
to observe living material must be considered a major
milestone in the advance of our understanding of the
mechanisms oflife.
Huge numbers of important observations have been made using
this instrument, but unfortunately it only produces two-
dimensional images.
The advent of the ELECTRON MICROSCOPE - first the
TRANSMISSION ELECTRON MICROSCOPE (TEM) and then the SCANNING
ELECTRON MICROSCOPE (SEM) made it possible to observe the
three-dimensional structure of specimen, literally adding a
whole new dimension to our understanding and bringing about
a second major milestone in microscopy. With their highly
specificarchitecture and great functional significance, the
respiratory apparatus and the airways have received
particluar atttention, and extensive series of
investigations with SEM have been done. |
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