This book presents selected papers from the 6th International Conference on Inventive Systems and Control (ICISC 2022), held on 6-7 January 2022 at JCT College of Engineering and Technology, Coimbatore, India. The conference proceedings of ICISC 2022 includes an analysis of the class of intelligent systems and control techniques that utilizes various artificial intelligence technologies, where there is no mathematical models and system available to make them remain controlled. Inspired by various existing intelligent techniques, the primary goal of ICISC 2022 proceedings is to present the emerging innovative models to tackle the challenges faced by the existing computing and communication technologies.