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Lieferstatus:	i.d.R. innert 14-24 Tagen versandfertig
Veröffentlichung:	Februar 2011
Genre:	Naturwissensch., Medizin, Technik
	Biochemie u. Chemische Biologie / Biochemistry (Chemical Biology) / Chemie / Chemische Biologie / chemistry
ISBN:	9780470711996
EAN-Code:	9780470711996
Verlag:	John Wiley and Sons Ltd
Einband:	Gebunden
Sprache:	English
Dimensionen:	H 222 mm / B 279 mm / D 61 mm
Gewicht:	3952 gr
Seiten:	965
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

Highlights the progress made in finding new and exciting metalloproteins 10 years after the original publication of the Handbook of Metalloproteins Volumes 1 & 2, and following publication of Volume 3 in 2004, comes the latest two volumes... Presents detailed descriptions of the most exciting newly discovered metalloproteins, including: * New metalloproteins involved in photosynthesis, e.g. photosystem I and II, cytochromes * New Copper Metalloproteins involved in the formation of Alzheimer's disease and are leads to new medication * New metalloproteins essential in understanding the function of nerves and muscles Researching the structure and function of metalloproteins is one of the biggest challenges in modern biological chemistry - and several Nobel Prizes have been awarded to research in the field, including to the Co-Editor Robert Huber in 1988. Volumes 4 & 5 help bring together the very latest new and exciting metalloproteins in two volumes to help keep you up-to-date in this continually expanding field, including: * New metalloproteins involved in photosynthesis Photosynthesis is vital for life on earth. Contributions on photosystem I and II as well as on cytochrome b6f, which are main components of the oxygenic photosynthetic machinery in plants, algae and cyanobacteria, unravel the role of metals and metal cofactors in this fascinating fundamental process * New Copper Metalloproteins The role of copper in connection with the amyloid precursor protein for Alzheimer's disease * New metalloproteins essential in understanding the function of nerves and muscles Contributions on Mg2+, Na+ and K+ channels/transporters have been included to highlight their formidable significance in biological systems. Na+, K+-ATPase is e.g. very abundant in heart muscle tissues and represents the target for drugs against heart insufficiency like digitalis drugs * Metalloproteins used in metal ion transport and storage Metal ion transport, storage and incorporation have been deeper considered in a row of new articles. The metal ions include iron, zinc, nickel and copper. * Factor VIII Factor VIII is an essential blood clotting factor. Some defects might cause a lack of this factor and result in hemophelia A. The new two volumes contain articles published online in the Handbook of Metalloproteins (HMET) from 2007 - 2010, these cover a wide range of newly discovered and exciting metalloproteins since publication of HMET in 2006. These new additional volumes will provide essential reading to all experienced researchers in bioinorganic chemistry and should give the newcomer a good entry into the field in the following areas: Metalloproteins, Proteins, Proteomics, Coordination Chemistry, Bioinorganic Chemistry, Biochemistry, Drug Development, Enzymology.