This book explores entrepreneurship from regions around the globe to enhance our policy and practical knowledge about the unique regional context in which entrepreneurs operate and demonstrate the importance of geography to entrepreneurial activity. Regions with diverse regional, industrial, and temporal contexts are explored and compared. Chapters explore a range of topics, such as patterns of regional/subnational variations in entrepreneurial activity, geographically mediated determinants of entrepreneurship, inter-temporal dynamics, evolution of regional systems of entrepreneurship, the impact of entrepreneurship on regional development and regional entrepreneurship policy.