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Lieferstatus:	i.d.R. innert 7-14 Tagen versandfertig
Veröffentlichung:	September 2020
Genre:	Naturwissensch., Medizin, Technik
	antisenseoligonucleotides / drugdevelopment / Gapmer-mediateddegradation / Gapmertherapeutics / Genesilencing / RNAdegradation
ISBN:	9781071607701
EAN-Code:	9781071607701
Verlag:	Humana
Einband:	Gebunden
Sprache:	English
Serie:	#2176 - Methods in Molecular Biology
Dimensionen:	H 260 mm / B 183 mm / D 20 mm
Gewicht:	693 gr
Seiten:	260
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This volume presents a comprehensive collection of detailed state-of-the-art protocols for gapmer-mediated RNA knockdown from leaders in the field. Chapters detail a historical and contemporary perspective of RNase H-inducing antisense oligonucleotides called gapmers and gapmer-mediated RNA knockdown for basic research and therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Gapmers: Methods and Protocols aims to provide diverse applications of gapmers along with protocols that will assist readers in moving the frontier.