"This book deals with combinatorial aspects of epistasis, especially normalized epistasis, a concept that exists in genetics and evolutionary algorithms. It starts with the theory of evolutionary algorithms. This illustrative introduction makes the book readable independent on other textbooks. . The book is very well written and presents many important and useful results. . It shows also that difficult practical problems can only be efficiently solved by a combination of Modelling, Mathematics and Computing." (Christian Posthoff, Zentralblatt MATH, Vol. 1108 (10), 2007)