Despite traumatic brain injury (TBI) being a leading cause of morbidity and mortality in the U.S., substantial unmet needs persist in TBI prevention, diagnosis, treatment, and recovery. The National Academies Forum on Traumatic Brain Injury hosted a public workshop in April 2024 to explore examples of recent research, development, and implementation of TBI diagnostic biomarkers, injury prevention technologies, clinical decision tools, and treatment approaches. Discussions explored examples of needs, opportunities, and challenges influencing innovation.