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Lieferstatus:	i.d.R. innert 14-24 Tagen versandfertig
Veröffentlichung:	Juli 2017
Genre:	Naturwissensch., Medizin, Technik
	B / Biomedical and Life Sciences / Biomedical Research / Cancer Research / Cancer;Carcinogen;Metal;Molecular medicine;Treatment / Medical research / molecular biology / Molecular Medicine
ISBN:	9783319554464
EAN-Code:	9783319554464
Verlag:	Springer International Publishing
Einband:	Gebunden
Sprache:	English
Serie:	Molecular and Integrative Toxicology
Dimensionen:	H 241 mm / B 160 mm / D 18 mm
Gewicht:	573 gr
Seiten:	240
Zus. Info:	HC runder Rücken kaschiert
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This book aims to present current state of understanding of the role of metals in human health and disease. As it will be difficult to cover all of the metals, about two scores of them, the authors will instead provide a detailed analysis of a select set of essential (Calcium, Magnesium, Selenium, Iron, copper and Zinc) and non-essential metals (Nickel, Chromium, Cadmium and Arsenic, Tungsten and Asbestos). Each chapter will have a dedicated section focusing on the binary role that some of these metals play, their carcinogenic and cancer therapeutics, by integrating epidemiological, experimental evidence with special emphasis and focus on molecular mechanisms involved in these processes. The biological analysis will also include emerging lines of evidence such as micro RNAS, kinase families, receptors, endoplasmic, mitochondrial players and epigenetics. As part of integrating the human, experimental and mechanistic data, as well as a detailed analysis into the modes of actionfor different cancer outcomes will be discussed in each chapter wherever deemed feasible. These approaches are ones in which no other book in this area has attempted to do.