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Compendium of In Vivo Monitoring in Real-Time Molecular Neuroscience: Volume 2: Microdialysis and Sensing of Neural Tissues
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(Buch) |
Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 3 Artikel!
Lieferstatus: |
i.d.R. innert 14-24 Tagen versandfertig |
Veröffentlichung: |
Juni 2017
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Genre: |
Naturwissensch., Medizin, Technik |
ISBN: |
9789813220539 |
EAN-Code:
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9789813220539 |
Verlag: |
Wspc |
Einband: |
Gebunden |
Sprache: |
English
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Dimensionen: |
H 250 mm / B 175 mm / D 27 mm |
Gewicht: |
909 gr |
Seiten: |
424 |
Zus. Info: |
HC gerader Rücken kaschiert |
Bewertung: |
Titel bewerten / Meinung schreiben
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Inhalt: |
Volume 1 of this series focused mainly on small molecules which are intrinsically electroactive. Volume 2 continues to provide current approaches to real time measurements of essential species in the central nervous system. It describes microdialysis, a sampling technique, which facilitates the removal of small volumes of solution containing the analyte(s) of interest which can be subsequently separated by chromatography and analyzed by a range of techniques. These include electrochemistry, UV-Vis spectroscopy, fluorescence and mass spectroscopy. This approach affords the opportunity to measure a range of targets in real-time thus providing access to pharmacokinetic/pharmacodynamics measurements affording the possibility of measuring the disappearance of a drug after administration and the subsequent appearance of metabolites. Microdialysis further affords the ability to sample peptides and proteins of neurobiological interest.
Consistent with the goals of Volume 1, Volume 2 seeks to provide for scientists in the field of neurobiology a base of bioanalytical techniques that may not be familiar to them. Specific examples are provided and the fundamental basis of the technique is also covered. |
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