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Herausgeber: 
  • Adrian C Michael
  • George S Wilson
  • Compendium of In Vivo Monitoring in Real-Time Molecular Neuroscience: Volume 2: Microdialysis and Sensing of Neural Tissues 
     

    (Buch)
    Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 3 Artikel!


    Übersicht

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    Lieferstatus:   i.d.R. innert 14-24 Tagen versandfertig
    Veröffentlichung:  Juni 2017  
    Genre:  Naturwissensch., Medizin, Technik 
    ISBN:  9789813220539 
    EAN-Code: 
    9789813220539 
    Verlag:  Wspc 
    Einband:  Gebunden  
    Sprache:  English  
    Dimensionen:  H 250 mm / B 175 mm / D 27 mm 
    Gewicht:  909 gr 
    Seiten:  424 
    Zus. Info:  HC gerader Rücken kaschiert 
    Bewertung: Titel bewerten / Meinung schreiben
    Inhalt:
    Volume 1 of this series focused mainly on small molecules which are intrinsically electroactive. Volume 2 continues to provide current approaches to real time measurements of essential species in the central nervous system. It describes microdialysis, a sampling technique, which facilitates the removal of small volumes of solution containing the analyte(s) of interest which can be subsequently separated by chromatography and analyzed by a range of techniques. These include electrochemistry, UV-Vis spectroscopy, fluorescence and mass spectroscopy. This approach affords the opportunity to measure a range of targets in real-time thus providing access to pharmacokinetic/pharmacodynamics measurements affording the possibility of measuring the disappearance of a drug after administration and the subsequent appearance of metabolites. Microdialysis further affords the ability to sample peptides and proteins of neurobiological interest. Consistent with the goals of Volume 1, Volume 2 seeks to provide for scientists in the field of neurobiology a base of bioanalytical techniques that may not be familiar to them. Specific examples are provided and the fundamental basis of the technique is also covered.

      



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