Volume 12

Compendium of Organic Synthetic Methods

Michael B. Smith

A handy desktop reference for organic chemists to browse new reactions and transformations of interest

The Compendium of Organic Synthetic Methods series facilitates the working chemist's search for the most useful functional group transformations in organic chemistry. Drawn from a comprehensive survey of the literature from 2002, 2003, and 2004, Compendium of Organic Synthetic Methods, Volume 12 contains both functional group transformations and carbon-carbon bond-forming reactions, as well as a chapter devoted exclusively to difunctional compounds. Author Michael Smith uses criteria for listing reactions that examines the real synthetic utility of the reaction, as well as the use of reagents that are either readily available or easily prepared and handled in the laboratory.

Among many other subjects, Volume 12 covers:

• Acid derivatives and anhydrides

• Alcohols

• Alkyls, methylenes, and aryls

• Amides

• Ethers, epoxides, and thioethers

• Halides and sulfonates

• Hydrides

• Alkenes

• Oxides

• Difunctional compounds

• Enantioselectivity and/or

Volume 12 presents about 2,500 examples of published reactions for the preparation of monofunctional compounds, updating the more than 15,500 examples in Volumes 1-11. It also contains about 1,500 examples of reactions for preparing difunctional compounds within various functional groups, and adds ninety seven pertinent reviews, long a feature of this series, in various sections. A useful alphabetical list of all cited authors follows chapter 16.

The organizational scheme classifies chemical transformations first by reaction of the functional group of starting material, then by functional group formed in order to provide for quick reference and information retrieval. In addition, indices for mono- and difunctional compounds efficiently guide the user to specific classes of transformations.

Compendium of Organic Synthetic Methods, Volume 12 provides a highly focused source of information on the methods, reactions, and transformations in contemporary organic chemistry for the working chemist and student alike.