The 43 revised full papers and 22 revised poster papers presented together with 4 invited lectures were carefully reviewed and selected from 78 submissions. The papers focus on challenging problems and new research not only in theoretical but application aspects of cellular automata, including cellular automata tools and computational sciences. The volume also contains 11 extended abstracts dealing with crowds and cellular automata, which were presented during the workshop C&CA 2008. The papers are organized in topical sections on CA theory and implementation, computational theory, physical modeling, urban, environmental and social modeling, pedestrian and traffic flow modeling, crypto and security, system biology, CA-based hardware, as well as crowds and cellular automata.