The mechanisms involved in the stimulation of cardiac fibrosis are not fully understood.  In most cases the marginal attenuation of cardiac fibrosis as a result of a given therapy is a beneficial side-effect linked to other primary effects on other cells, especially cardiomyocytes.  Very few drugs or agents are known to affect the function and dysfunction of cardiac fibroblasts and myofibroblasts alone.  The book helps to translate the information gathered within to allow us to alter the course of fibrogenic events that are typical of cardiac fibrosis, and thereby reduce their burden on the patient and on society itself.