The aim of this book is to help clinicians, neuroscientists, as well as students, understand the significance of the endocannabinoid system. This book, however, also will be very useful to those who already feel comfortable with the neuroscience of endocannabinoids. The book will introduce the reader to the "up-to-date" neurobiology of endocannabinoids and related systems, and will detail their pathophysiological role and therapeutic potential. Authors involved in clinical investigations present results of recent clinical trials, and the development of new therapeutic strategies and medicines.