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Herausgeber: 
  • Nagy Habib
  • Cancer Gene Therapy: Past Achievements and Future Challenges 
     

    (Buch)
    Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 3 Artikel!


    Übersicht

    Auf mobile öffnen
     
    Lieferstatus:   Auf Bestellung (Lieferzeit unbekannt)
    Veröffentlichung:  April 2000  
    Genre:  Naturwissensch., Medizin, Technik 
     
    Animal anatomy / Animal Anatomy / Morphology / Histology / apoptosis;development;gene therapy;genes;transcription / Biomedical and Life Sciences / C / Human Genetics / Immunology / Medical Genetics / Oncology / Zoology & animal sciences
    ISBN:  9780306461910 
    EAN-Code: 
    9780306461910 
    Verlag:  Springer Nature EN 
    Einband:  Gebunden  
    Sprache:  English  
    Serie:  #465 - Advances in Experimental Medicine and Biology  
    Dimensionen:  H 234 mm / B 156 mm / D  
    Gewicht:  1980 gr 
    Seiten:  496 
    Bewertung: Titel bewerten / Meinung schreiben
    Inhalt:
    With the coming of the new millennium we are witnessing a revolution in our understanding of cancer genetics. These are very exciting times. Today we have at our disposal the technology to diagnose abnormalities in our cancer genes and the means to correct the deficit and very soon we will have the complete sequence of the human genome. With the use of gene chip technology the way doctors will be able to assess patients will change completely. Today we can diagnose abnormalities in ten thousand genes and within a short period of time we will be able to screen through our genome and discover potential abnormalities in our proto-oncogenes, tumour suppressor genes, differentiating genes, apoptotic genes and pro-inflammatory genes. In this book various authors have highlighted specific genes that could be expressed, overexpressed, neutralised or h- nessed to achieve cancer control. The problem of transferring the therapeutic gene into the cancer cell has been partly addressed with major developments in the field of naked plasmid DNA, adenovirus, retrovirus and adeno-associated viruses. However, further improvements are yet to be made to achieve significant gene transfer. Gene expression, in particular specificity of gene transfer, is obviously an important issue and one which is highlighted in this book by the use of specific promoter.
      
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