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CILP: Protein, Genetic Code, Macromolecule, Polysaccharide, Nucleic Acid, Enzyme, Catalysis
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Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 2 Artikel!
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| Please note that the content of this book primarily consists of articles
available from Wikipedia or other free sources online. Cartilage
intermediate layer protein 1 is a protein that in humans is encoded by
the CILP gene.Major alterations in the composition of the cartilage
extracellular matrix occur in joint disease, such as osteoarthrosis. The
synthesis of cartilage intermediate layer protein (CILP), which was
identified and purified from human articular cartilage, increases in
early osteoarthrosis cartilage. The C-terminal 460 amino acids of the
protein show 90% similarity to the pig ectonucleotide
pyrophosphohydrolase NTPPHase; this region is preceded by a furin
protease consensus cleavage site. Thus, the CILP gene is thought to
encode a protein precursor for 2 different proteins, namely CILP and a
homolog of NTPPHase. |
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i.d.R. innert 7-14 Tagen versandfertig
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