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CARD10: Protein, Genetic Code, Enzyme, Macromolecule, Polysaccharide, Nucleic Acid, Catalysis
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available from Wikipedia or other free sources online. Caspase
recruitment domain-containing protein 10 is an enzyme that in humans is
encoded by the CARD10 gene.The caspase recruitment domain (CARD) is a
protein module that consists of 6 or 7 antiparallel alpha helices. It
participates in apoptosis signaling through highly specific
protein-protein homophilic interactions. CARDs induce nuclear factor
kappa-B (NFKB; MIM 164011) activity through the IKK (e.g., IKBKB; MIM
603258) complex. CARD9 (MIM 607212), CARD10, CARD11 (MIM 607210), and
CARD14 (MIM 607211) interact with BCL10 (MIM 603517) and are involved in
NFKB signaling complexes. Except for CARD9, these CARD proteins are
members of the membrane-associated guanylate kinase (MAGUK) family. |
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