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Lieferstatus:	i.d.R. innert 7-14 Tagen versandfertig
Veröffentlichung:	August 2018
Genre:	Naturwissensch., Medizin, Technik
	B / biochemistry / Biomedical and Life Sciences / Bioorganic Chemistry / Engineering applications of bio-materials / Life Sciences / MEDICINAL CHEMISTRY / Neurochemistry / Neurology & clinical neurophysiology / Nucleic Acid Chemistry / Nucleic acids / ORGANIC CHEMISTRY / Pharmacology / Pharmacology/Toxicology / Protein-Ligand Interactions / proteins
ISBN:	9783319876801
EAN-Code:	9783319876801
Verlag:	Springer International Publishing
Einband:	Kartoniert
Sprache:	English
Serie:	#72 - Progress in Drug Research
Dimensionen:	H 235 mm / B 155 mm / D 14 mm
Gewicht:	388 gr
Seiten:	252
Zus. Info:	Paperback
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis, comparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can  be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy.