Übersicht			Auf mobile öffnen

Lieferstatus:	Auf Bestellung (Lieferzeit unbekannt)
Veröffentlichung:	November 2010
Genre:	Naturwissensch., Medizin, Technik
	Biomedical and Life Sciences / Biomedical Research / C / Cancer Research / Cell Biology / Cellular biology (cytology) / Developmental biology / Life Sciences / Oncology
ISBN:	9783642088650
EAN-Code:	9783642088650
Verlag:	Springer Nature EN
Einband:	Kartoniert
Sprache:	English
Serie:	#45 - Progress in Molecular and Subcellular Biology
Dimensionen:	H 235 mm / B 155 mm / D
Gewicht:	403 gr
Seiten:	248
Illustration:	XII, 248 p.
Zus. Info:	Previously published in hardcover
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

Cell biologists have recently become aware that the asymmetry of cell division is an important regulatory phenomenon in the fate of a cell. During development, cell diversity originates through asymmetry; in the adult organism asymmetric divisions regulate the stem cell reservoir and are a source of the drift that contributes to the aging of organisms with renewable cell compartments. Because of the concept of semi-conservative DNA synthesis, it was thought that the distribution of DNA between daughter cells was symmetric. The analysis of the phenomenon in cells during mitosis, however, revealed the asymmetry in the distribution of the genetic material that creates the drift contributing to aging of mammals. On the other hand, cancer cells can originate from a deregulation of asymmetry during mitosis in particular during stem cell expansion. The book describes the phenomenon in different organisms from plants to animals and addresses its implications for the development of the organism, cell differentiation, human aging and the biology of cancers.