The 200 revised full papers presented were carefully reviewed and selected from more than 300 submissions. The second volume is divided in topical sections on neuroinformatics and bioinformatics; cognitive machines; data analysis and pattern recognition; signal and time series processing; neural dynamics and complex systems; vision and image processing; neuro-evolution and hybrid techniques for mobile agents control; neural control, planning and robotics applications; intelligent tools and methods for multimedia annotation; and critical infrastructure systems.