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Herausgeber: 
  • Howard I. Maibach
  • Chantra Eskes
  • Erwin van Vliet
  • Alternatives for Dermal Toxicity Testing 
     

    (Buch)
    Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 3 Artikel!


    Übersicht

    Auf mobile öffnen
     
    Lieferstatus:   Auf Bestellung (Lieferzeit unbekannt)
    Veröffentlichung:  August 2018  
    Genre:  Naturwissensch., Medizin, Technik 
     
    Animal Models / Animal models in research / B / Dermatology / Experimental Organisms / Medicine / Pharmacology / Pharmacology/Toxicology
    ISBN:  9783319843780 
    EAN-Code: 
    9783319843780 
    Verlag:  Springer EN 
    Einband:  Kartoniert  
    Sprache:  English  
    Dimensionen:  H 235 mm / B 155 mm / D  
    Gewicht:  1242 gr 
    Seiten:  592 
    Illustration:  XX, 592 p. 92 illus., 61 illus. in color., schwarz-weiss Illustrationen, farbige Illustrationen 
    Bewertung: Titel bewerten / Meinung schreiben
    Inhalt:
    This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol, possible adaptations, and challenges and opportunities. The closing section addresses exploratory areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, the useof alternative methods for infections and inflammatory diseases, novel complex skin models, and high-throughput screening techniques.

    Dermal toxicity is an area in which alternatives to the use of animal testing have already gained scientific, industrial, and regulatory acceptance. Practitioners and researchers alike will find Alternatives for Dermal Toxicity Testing to be an ideal source of reliable, up-to-date information on all aspects of the available test methods and likely future directions.

      



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