This book constitutes the refereed proceedings of the 6th Industrial Conference on Data Mining, ICDM 2006, held in Leipzig, Germany in July 2006. Presents 45 carefully reviewed and revised full papers organized in topical sections on data mining in medicine, Web mining and logfile analysis, theoretical aspects of data mining, data mining in marketing, mining signals and images, and aspects of data mining, and applications such as intrusion detection, and more.