With an emphasis on the most up-to-date techniques commonly used in organic synthesis, this third edition reference draws on the extensive experience of the authors and their association with some of the world's leading laboratories of synthetic organic chemistry. Written mainly for graduate and advanced undergraduate students as well as industrial organic chemists, this book provides sufficient guidance to allow the researcher to carry out reactions under conditions that offer the highest chance of success. It offers fully updated information and re-drawn figures to illustrate the information at the highest possible standard.