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Autor(en): 
  • Alex Avdeef
  • Absorption 2e 
     

    (Buch)
    Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 3 Artikel!


    Übersicht

    Auf mobile öffnen
     
    Lieferstatus:   i.d.R. innert 14-24 Tagen versandfertig
    Veröffentlichung:  Mai 2012  
    Genre:  Naturwissensch., Medizin, Technik 
     
    Medical / Nursing / MEDICAL / Pharmacology / MEDICAL / Pharmacy / SCIENCE / Chemistry / Industrial & Technical
    ISBN:  9781118057452 
    EAN-Code: 
    9781118057452 
    Verlag:  Wiley 
    Einband:  Gebunden  
    Sprache:  English  
    Dimensionen:  H 240 mm / B 161 mm / D 44 mm 
    Gewicht:  1267 gr 
    Seiten:  744 
    Bewertung: Titel bewerten / Meinung schreiben
    Inhalt:
    Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug candidates. Moreover, the author provides expert guidance to help readers analyze the results of their studies in order to select the most promising drug candidates. This Second Edition has been thoroughly updated and revised, incorporating all the latest research findings, methods, and resources, including: * Descriptions and applications of new PAMPA models, drawing on more than thirty papers published by the author's research group * Two new chapters examining permeability and Caco-2/MDCK and permeability and the blood-brain barrier * Expanded information and methods to support pKa determination * New examples explaining the treatment of practically insoluble test compounds * Additional case studies demonstrating the use of the latest physicochemical techniques * New, revised, and expanded database tables throughout the book Well over 200 drawings help readers better understand difficult concepts and provide a visual guide to complex procedures. In addition, over 800 references serve as a gateway to the primary literature in the field, facilitating further research into all the topics covered in the book. This Second Edition is recommended as a reference for researchers in pharmaceutical R&D as well as in agrochemical, environmental, and other related areas of research. It is also recommended as a supplemental text for graduate courses in pharmaceutics.

      



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