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Lieferstatus:	i.d.R. innert 14-24 Tagen versandfertig
Veröffentlichung:	Juni 2018
Genre:	Naturwissensch., Medizin, Technik
	B / Biomedical engineering / Biomedical Engineering and Bioengineering / Electronic circuits / Electronic Circuits and Devices / Electronic Circuits and Systems / Electronic devices & materials / Materials science / Materials—Surfaces / Medical Genetics / Microarrays / Physics and Astronomy / Polymer chemistry / Polymer Sciences / polymers / Surface chemistry & adsorption / Surfaces and Interfaces, Thin Films / Surfaces, Interfaces and Thin Film / Thin films
ISBN:	9789811304712
EAN-Code:	9789811304712
Verlag:	Birkhäuser Boston
Einband:	Gebunden
Sprache:	English
Serie:	Springer Theses
Dimensionen:	H 241 mm / B 156 mm / D 15 mm
Gewicht:	334 gr
Seiten:	88
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

This book describes the design, fabrication and evaluation of a polymer-based neural interface for a cochlear electrode array, reviewed in terms of fabrication process, functionality, and reliability. Polymer-based devices have attracted attention in the neural prosthetic field due to their flexibility and compatibility with micro-fabrication process. A liquid crystal polymer (LCP) is an inert, highly water-resistant polymer suitable for the encapsulation of electronic components and as a substrate material for fabricating neural interfaces. The author has designed, fabricated, and evaluated an LCP-based cochlear electrode array for an improved polymer-based cochlear implant. The thesis deals with 3 key topics: atraumatic deep insertion, tripolar stimulation, and long-term reliability. Atraumatic insertion of the intracochlear electrode and resulting preservation of residual hearing have become essential in state-of-the-art cochlear implantation. A novel tapered design of an LCP-based cochlear electrode array is presented to meet such goals. For high-density and pitch-recognizable cochlear implant, channel interaction should be avoided. Local tripolar stimulation using multi-layered electrode sites are shown to achieve highly focused electrical stimulation. This thesis addresses another vital issue in the polymer-based neural implants: the long-term reliability issue. After suggesting a new method of forming mechanical interlocking to improve polymer-metal adhesion, the author performs accelerating aging tests to verify the method's efficacy. The aforementioned three topics have been thoroughly examined through various in vitro and in vivo studies. Verification foresees the development of LCP-based cochlear electrode array for an atraumatic deep insertion, advanced stimulation, and long-term clinical implant.