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Lieferstatus:	i.d.R. innert 7-14 Tagen versandfertig
Veröffentlichung:	November 2015
Genre:	Naturwissensch., Medizin, Technik
ISBN:	9783659802737
EAN-Code:	9783659802737
Verlag:	LAP Lambert Academic Publishing
Einband:	Kartoniert
Sprache:	English
Dimensionen:	H 220 mm / B 150 mm / D 8 mm
Gewicht:	215 gr
Seiten:	132
Zus. Info:	Paperback
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

Bancroftian filariasis is caused in human by Wuchereria (W.) bancrofti, which has major antigenic sharing with Dirofilaria (D.) immitis and Setaria (S.) equina. S. equina was used for diagnosis of bancroftian filariasis in human in comparison to D. immitis. Serological diagnosis of filariasis is generally more reliable than detection of microfilaria (mf) in blood samples. S. equina antigen was prepared from the adult worm. Fractionation of both whole S. equina crude antigen and imported D. immitis was done by polyacrylamide gel electrophoresis. The two antigens shared the same band pattern of 112 kDa. Ninety two Egyptian individuals were grouped in the present study. Anti-filarial antibodies were detected among different studied groups in the serum samples tested by indirect ELISA technique. The sensitivity of the indirect ELISA using crude S. equina, purified S. equina and D. immitis antigens was 78.6%, 85.71% and 80.95%, while specificity was 66%, 76% and 80%, respectively. Detection of circulating filarial antigen in different studied groups using anti-purified S. equina IgG was measured by sandwich ELISA, the sensitivity of the assay was 80.95% and 92.0% specificity.