This volume discusses how biosurveillance systems support epidemiologists and public health officials in the early identification, situational awareness, and response management of natural and man-made health-related events. Initial chapters build a foundation while subsequent chapters present applied case studies from around the world, including China, the United States, Denmark, and the Asia-Pacific region. Through these case studies, the expert contributors offer first-hand insight on lessons learned and unresolved issues. The book also addresses policy and organizational issues related to the construction of biosurveillance systems.