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  • W. E. Castle
  • Piebald Rats and Selection: An Experimental Test of the Effectiveness of Selection and of the Theory of Gametic Purity in Mendelian Crosses (Classic R 

    Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 2 Artikel!

    Lieferstatus:   i.d.R. innert 5-10 Tagen versandfertig
    Veröffentlichung:  August 2015  
    Genre:  Naturwissensch., Medizin, Technik 
    ISBN:  9781332300389 
    Verlag:  Forgotten Books 
    Einband:  Kartoniert  
    Sprache:  English  
    Dimensionen:  H 229 mm / B 152 mm / D 4 mm 
    Gewicht:  105 gr 
    Seiten:  68 
    Zus. Info:  23:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on White w/Gloss Lam 
    Bewertung: Titel bewerten / Meinung schreiben
    Excerpt from Piebald Rats and Selection: An Experimental Test of the Effectiveness of Selection and of the Theory of Gametic Purity in Mendelian Crosses The fundamental importance of Mendel's law of heredity is generally recognized among biologists. It is a working hypothesis whose utility is fully substantiated by abundant results daily increasing in amount. But biologists are not in agreement as to how much this law includes. All perhaps would agree that it implies the existence in the germ-cell of specific determiners essential for the production of particular characteristics in the offspring. Further, no one probably will object to the statement that it implies a dual or duplex condition of the zygote as regards determiners and a simple or simplex condition of the gamete. Thirdly, the fact will be admitted by all that most mendelizing characters are wholly independent of each other in heredity, for which reason we are forced to suppose that their determiners are distinct within the germ-cell. But beyond these few generalizations great diversity of opinion exists. As regards the very nature and function of the determiners, some consider them unvarying, and explain the observed variation of mendelizing characters in organisms as due to a modifying action of other determiners. At one time even a modifying action of other determiners was denied, and the theory was advanced that the gametes extracted from a mendelian cross are pure as regards the single characters which may have been concerned in that cross. Investigations carried out by Castle have done something to dispel this idea. In particular it was shown (Castle, 1905, 1906; Castle and Forbes, 1906) that in guinea-pigs, polydactylism, long-hair, and rough coat are mendelizing characters which are affected in the degree of their development by crosses - that is, when these characters are "extracted" from crosses the characters are not exactly the same as before; hence the gametes are not "pure." The experimental result is not denied, but in order to save the substance of the theory its advocates now suppose that the determiners have not changed, but in consequence of the cross certain modifiers have become associated with them which change their appearance in the organism. The real unchanging thing is now called the "genotype," its appearance the "phenotype." In this genotype theory we are dealing only with a new and more refined aspect of the "theory of pure gametes." It is not a necessary part of mendelism, not even an original part; but it is very important for us to know whether it is true or not. For if it is true, selection unattended by hybridization is largely a waste of time, as De Vries and Johannsen have maintained, and Jennings and Pearl have reiterated. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.

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