Übersicht			Auf mobile öffnen

Lieferstatus:	Auf Bestellung (Lieferzeit unbekannt)
Veröffentlichung:	Dezember 2017
Genre:	Naturwissensch., Medizin, Technik
	B / Biomedical and Life Sciences / Cell Biology / Human Genetics / Medical Genetics
ISBN:	9789811066733
EAN-Code:	9789811066733
Verlag:	Springer Nature EN
Einband:	Gebunden
Sprache:	English
Serie:	#1038 - Advances in Experimental Medicine and Biology
Dimensionen:	H 235 mm / B 155 mm / D
Gewicht:	5287 gr
Seiten:	230
Illustration:	VII, 230 p. 89 illus., 62 illus. in color., schwarz-weiss Illustrationen, farbige Illustrationen
Bewertung:	Titel bewerten / Meinung schreiben

Inhalt:

The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing.  Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinicalstudents and researchers in the field of mtDNA-associated diseases.