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Autor(en): 
  • Archana Sharma
  • Rajeev Kharb
  • Rajan Chauhan
  • Design, In-silico and ADME Studies: Triazole Bearing Quinolone Molecular Hybrids as Antimicrobial Agents 
     

    (Buch)
    Dieser Artikel gilt, aufgrund seiner Grösse, beim Versand als 2 Artikel!


    Übersicht

    Auf mobile öffnen
     
    Lieferstatus:   i.d.R. innert 7-14 Tagen versandfertig
    Veröffentlichung:  September 2021  
    Genre:  Naturwissensch., Medizin, Technik 
    ISBN:  9786204208404 
    EAN-Code: 
    9786204208404 
    Verlag:  LAP Lambert Academic Publishing 
    Einband:  Kartoniert  
    Sprache:  English  
    Dimensionen:  H 220 mm / B 150 mm / D 8 mm 
    Gewicht:  197 gr 
    Seiten:  120 
    Zus. Info:  Paperback 
    Bewertung: Titel bewerten / Meinung schreiben
    Inhalt:
    Antimicrobial resistance is a global public health problem that challenges our ability to treat bacterial infections effectively. Microorganisms that are treated with anti-microbial drugs increase their fitness against these drugs by acquiring and expressing resistance genes and spread these genes to other microorganisms through Darwinian selection. In order to have a drug that is effective against these microorganisms, we have to synthesize a new range of antimicrobials having different modes of action to solve the problem of microbial resistance towards the currently used antibiotics. A new strategy has been utilized by the researchers in which a new compound is designed by combining two different pharmacophores which are previously known to be effective against these microorganisms. The synthesized compound would have a synergistic effect and both pharmacophores will be having different modes of action so that the microorganism does not develop resistance towards such hybrid compound. In this book, we have presented design, In-silico, and ADME studies of triazole-bearing quinolone molecular hybrids as antimicrobial agents.

      
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